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ONL Therapeutics is a privately held biotech company delivering on commitments to its investors to accelerate clinical development of first-in-class therapeutics

In September 2024, the company closed on a $65 million oversubscribed Series D round financing round. Johnson & Johnson Innovation – JJDC, Inc. led the round that was backed by a consortium of investors that included Bios Partners, Novartis Venture Fund, Visionary Ventures, and ExSight Ventures, amongst others. Proceeds from the Series D will advance the development of ONL1204 Ophthalmic Solution into a Phase 2 global study for the treatment of geographic atrophy (GA) associated with dry age-related macular degeneration (AMD).

In August 2023, the company closed on a $15 million Series C Preferred Stock financing round, primarily to support the advancement of its lead compound ONL1204 Ophthalmic Solution into a Phase 2 clinical trial in patients with macula-off rhegmatogenous retinal detachment (RRD). The financing was led by Bios Partners and included new investors Visionary Ventures, Alpine Visionary Ventures and Mayewell Capital, as well as existing investors Johnson & Johnson Innovation – JJDC, Inc., Kaitai Capital, PSQ Capital, Michigan Capital Network Venture Fund III, ExSight Ventures, the University of Michigan’s Michigan Investment in New Technology Startups (MINTS) program, Western Michigan University’s Biosciences Research & Commercialization Center, and the Capital Community Angels.

In December 2020, the company closed a $46.8 million Series B round, with Bios Partners leading, joined by fellow new investors Johnson & Johnson Innovation – JJDC, Inc., Kaitai Capital, InFocus Capital Partners, ExSight Ventures, and Michigan Capital Network Venture Fund III. Proceeds from the Series B financing enabled ONL to complete a Phase I clinical study of ONL1204 in retinal detachment and advance ONL1204 in two chronic indications, glaucoma and geographic atrophy associated with dry age-related macular degeneration.

In prior financing, the company completed a $4.25 million Series A financing round that involved both existing and new investors including Novartis, the University of Michigan’s Michigan Investment in New Technology Startups (MINTS) program, Capital Community Angels, Invest Michigan, Biosciences Research & Commercialization Center and Hestia Investments.


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